A clinical case of early coronary atherosclerosis complicated by acute myocardial infarction in a young man with unspecified familial hypercholesterolemia
Familial hypercholesterolemia (FH) is a hereditary autosomal dominant disorder characterized by elevated low-density lipoprotein (LDL) levels and decreased numbers of functioning receptors for them. A serious complication of FH is systemic atherosclerosis, which occurs in young people, and even children, who do not have risk factors for cardiovascular diseases (CVD). Untimely diagnosis, lack of specific treatment can lead to the development of premature acute myocardial infarction (AMI) and stroke, early cardiovascular death or disability of patients. The authors present a description of a case of early coronary atherosclerosis complicated by AMI in a young man 37 years old with unspecified FH.L.V. Tarasova, L.A. Porfiryeva, O.V. Dimitrieva, N.Yu. Kucherova
Keywords
familial hypercholesterolemia
early atherosclerosis
young age
coronary artery disease
acute myocardial infarction
About the Authors
Larisa V. Tarasova, Dr. Sci. (Med.), Associate Professor, Head of the Department of Faculty and Hospital Therapy, I.N. Ulyanov Chuvash State University; Professor at the Department of Public Health and Healthcare, Institute for Advanced Medical Education; Head of the Gastroenterology Department, Republican Clinical Hospital, Cheboksary, Russia; tlarisagast18@mail.ru, ORCID: https://orcid.org/0000-0003-1496-0689 (corresponding author)Liana A. Porfirieva, post-graduate student, Department of Faculty and Hospital Therapy, I.N. Ulyanov Chuvash State University; Cardiologist at the Cardiology Department No. 4, Republican Cardiology Dispensary, Cheboksary, Russia; krasnova-liana@mail.ru, ORCID: https://orcid.org/0009-0009-0256-9704
Olga V. Dimitrieva, Cand. Sci. (Med.), Associate Professor of the Department of Hospital Therapy, I.N. Ulyanov Chuvash State University; Cardiologist, Republican Cardiology Dispensary, Cheboksary, Russia; salgarii@mail.ru ORCID: https://orcid.org/0000-0002-7771-6141
Nadezhda Yu. Kucherova, post-graduate student, Department of Faculty and Hospital Therapy, I.N. Ulyanov Chuvash State University, Cardiologist, Republican Cardiology Dispensary, Cheboksary, Russia; nadezda_kan@mail.ru, ORCID: https://orcid.org/0000-0002-9500-3719