To cure or to help recover? (literature review)
Kulchavenya E.V.
Modern patients typically have multiple morbidities, leading to polypharmacy, which can have extremely unpleasant consequences. Recently, Host Directed Therapeutics (HDTs) – treatments aimed at the macroorganism, allowing a person to recover by stimulating their own defenses and normalizing homeostasis – have become increasingly popular. In particular, restoring the balance of the antioxidant system promotes recovery from many diseases.
This review presents data on the effectiveness of exogenous antioxidant factors, both non-enzymatic low-molecular compounds (vitamins A, E, and C) and microelements (selenium, zinc).
Conclusion: The modern pharmacopoeia allows for the treatment of virtually any disease, but the associated damage can be significant. Recent studies have shown that in some cases, the body can recover on its own, with minimal support aimed at normalizing the immune system, redox balance, local cytokine therapy, and secretome correction.
For citations: Kulchavenya E.V. To cure or to help recover? (literature review) Pharmateca. 2026;33(6):108-116. (In Russ.). DOI:
https://dx.doi.org/10.18565/pharmateca.2026.6.108-116
Authors’ contribution: E.V. Kulchavenya – concept and design of the review, literature search and analysis, writing and editing the text, approval of the final version of the article.
Conflicts of interest: The authors confirm that they have no conflicts of interest to declare.
Funding: The study was conducted without any sponsorship.
Keywords
chronic prostatitis/chronic pelvic pain syndrome
infertility
pathogenetic therapy
selenium
zinc
antioxidant system
oxidative stress
Selzinc Plus
About the Authors
Ekaterina V. Kulchavenya, Dr. Sci. (Med.), Professor at the Department of Phthisiopulmonology, Novosibirsk State Medical University; Scientific Director of the Department of Urology, Avicenna Clinical Hospital, Mother and Child Group of Companies, Novosibirsk, Russia; urotub@yandex.ru, ORCID: https://orcid.org/0000-0001-8062-7775, eLibrary SPIN: 5244-4960, Scopus Author ID: 6505712683Similar Articles
