A modern methodology for examining individuals with dyslipoproteinemia
Derbeneva S.A., Shmeleva S.V., Belyakova N.V., Aralova E.V.
Background: The nutritional status (NS) of individuals with hyperlipoproteinemia (HLP), including parameters of body composition, energy metabolism, and macronutrient metabolism, has not been fully studied.
Objective: Determination of NS characteristics in individuals with different types of atherogenic HLP and development of an algorithm for the early diagnosis of lipid metabolism disorders and the development and progression of atherosclerosis.
Materials and methods: A NS study was conducted in 956 patients with cardiovascular diseases, divided into groups based on the type of hyperlipidemia. This study included anthropometric examination, examination of body composition, macronutrient/energy metabolism parameters, and NS biomarkers, as well as determination of the actual dietary patterns at home.
Results: Individuals with different types of atherogenic hyperlipidemia exhibit differences in their clinical status and NS, as well as the risk of developing complications. Therefore, accurate diagnosis of existing disorders and, accordingly, their timely correction are required.
Conclusion: A methodology for a step-by-step examination of individuals with dyslipoproteinemia at different stages of medical care in healthcare facilities in the Russian Federation has been developed and tested.
For citations: Derbeneva S.A., Shmeleva S.V., Belyakova N.V., Aralova E.V. A modern methodology for examining individuals with dyslipoproteinemia. Pharmateca. 2025;32(8):148-152. (In Russ.). DOI: https://dx.doi.org/10.18565/pharmateca.2025.8.148-152
Authors’ contribution: S.A. Derbeneva – study design, writing, data collection. N.V. Belyakova and E.V. Aralova processed the material and conceptualized the study. S.V. Shmeleva edited and compiled the reference list. All authors are responsible for the integrity of the manuscript and approve the final version.
Conflicts of interest: The authors confirm that they have no conflicts of interest to declare.
Funding: Federal budget. The study was conducted as part of a state assignment for the Federal Research Center for Nutrition and Biotechnology.
Ethical Approval: The study was approved by the Ethics Committee of K.G. Razumovsky Moscow State University of Technology and Management, Protocol No. 5 dated March 20, 2025.
Patient Consent for Publication: All patients provided informed consent for the publication of their data.
Authors’ Data Sharing Statement: The data supporting the findings of this study are available upon request from the corresponding author after approval from the principal investigator.
Keywords
cardiovascular diseases
dyslipoproteinemia
hyperlipoproteinemia
nutritest
examination algorithm
About the Authors
S.A. Derbeneva, Dr. Sci. (Med.), Federal Research Center for Nutrition and Biotechnology, Moscow, Russia; ORCID: https://orcid.org/0000-0003-1876-1230S.V. Shmeleva, Dr. Sci. (Med.), Professor, K.G. Razumovsky Moscow State University of Technology and Management (First Cossack University), Moscow, Russia; 89151479832@mail.ru, ORCID: https://orcid.org/0000-0003-0390-194X (corresponding author)
N.V. Belyakova, K.G. Razumovsky Moscow State University of Technology and Management (First Cossack University), Moscow, Russia; ORCID: https://orcid.org/0000-0001-7116-9389
E.V. Aralova, K.G. Razumovsky Moscow State University of Technology and Management (First Cossack University), Moscow, Russia; ORCID: https://orcid.org/0000-0001-7835-8756
Similar Articles
