The concept of multimodal efficacy of vasoactive nootropics based on nicotinoyl gamma-aminobutyric acid in the treatment and rehabilitation of various populations (literature review and personal experience)
Tarantzova A.V.
This article summarizes scientific data and presents a systemic analysis of the long-term practical use of an original Russian nootropic based on nicotinoyl-gamma-aminobutyric acid (nicotinoyl-GABA) in various fields of medicine. This nootropic possesses multiple pharmacological effects, including vasoactive, neuroprotective, and antioxidant effects. A key contradiction between the significant volume of positive clinical data on efficacy and the lack of inclusion of nicotinoyl-GABA-based drugs in Russian and international treatment standards and clinical guidelines is identified necessitating filling the gaps in the evidence base. The study’s uniqueness lies in its global analytical approach, integrating historical aspects of the drug’s development and implementation, its pharmacological characteristics, modern clinical and experimental studies, and new methods of drug administration (physiotherapeutic drug electrophoresis). The author’s experience with the drug is presented, and the prospects for expanding its use in therapy and medical rehabilitation are substantiated.
For citations: Tarantzova A.V. The concept of multimodal efficacy of vasoactive nootropics based on nicotinoyl gamma-aminobutyric acid in the treatment and rehabilitation of various populations (literature review and personal experience). Pharmateca. 2026;33(3):38-63. (In Russ.). DOI: https://dx.doi.org/10.18565/pharmateca.2026.3.38-63
Conflicts of interest: The authors confirm that they have no conflicts of interest to declare.
Funding: The study was conducted without any sponsorship.
Keywords
nicotinoyl-gamma-aminobutyric acid (nicotinoyl-GABA)
multimodal nootropic
therapy
physiotherapy
medical rehabilitation
About the Authors
Aleksandra V. Tarantsova, Cand. Sci. (Med.), Physiotherapist, General Practitioner, Nadezhda (MDC DonZdrav), Rostov-on-Don, Russia; alexandrina-2015@mail.ru, ORCID: https://orcid.org/0000-0003-1447-1973Similar Articles
