Herbal medicines in the treatment of acute respiratory infections: current aspects of using combination therapies based on thyme, ivy, and primrose

Kolosova N.G., Shatalina S.I.

I.M. Sechenov First Moscow State University (Sechenov University), Department of Pediatric Diseases, N.F. Filatov Clinical Institute of Child Health, Moscow, Russia

Acute respiratory infections (ARIs) are the most common group of diseases, especially in pediatric practice. The main symptom of ARIs is cough, the pathogenesis of which is associated with damage to the ciliated epithelium and impaired mucociliary clearance. In the context of rational pharmacotherapy and the problem of antibiotic resistance, herbal medicines with proven efficacy are of particular interest. This article discusses the mechanism of action and therapeutic potential of the combination drug Bronchipret®, which contains extracts of thyme, ivy, and primrose. The drug’s components have been shown to have anti-inflammatory, expectorant, bronchodilator, and antiviral effects, and their combination provides a synergistic effect. Clinical studies confirm the effectiveness of this drug in the treatment of ARIs and reduce the frequency of antibiotic prescriptions. Its favorable safety profile and proven efficacy have led to its inclusion in clinical guidelines for the treatment of bronchitis and acute respiratory viral infections (ARVIs) in adults and children.

For citations: Kolosova N.G., Shatalina S.I. Herbal medicines in the treatment of acute respiratory infections: current aspects of using combination therapies based on thyme, ivy, and primrose. Pharmateca. 2026;32(7):106-111. (In Russ.). DOI: https://dx.doi.org/10.18565/pharmateca.2026.7.106-111

Authors’ contribution: N.G. Kolosova – development of the article’s concept, review of publications on the topic, drafting of the manuscript, and approval of the manuscript for publication. S.I. Shatalina – review of publications on the topic, drafting of the manuscript, and critical review of the content.
Conflicts of interest: The authors confirm that they have no conflicts of interest to declare.
Funding: The study was conducted without any sponsorship.

Keywords

About the Authors

Natalia G. Kolosova, Cand. Sci. (Med.), Associate Professor, Department of Pediatric Diseases, N.F. Filatov Clinical Institute of Child Health, I.M. Sechenov First Moscow State University (Sechenov University), Moscow, Russia; kolosovan@mail.ru, ORCID: https://orcid.org/0000-0001-5071-9302 (corresponding author)
Svetlana I. Shatalina, Cand. Sci. (Med.), Assistant Professor, Department of Pediatric Diseases, N.F. Filatov Clinical Institute of Child Health, I.M. Sechenov First Moscow State University (Sechenov University), Moscow, Russia; svetlanashatalina@mail.ru, ORCID: https://orcid.org/0000-0003-2085-0021

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