Moisturizing and antipruritic dermocosmetics in the treatment of atopic dermatitis during pregnancy

Kandrashkina Yu.A., Orlova E.A.

1) Penza State University, Department of Obstetrics and Gynecology, Penza, Russia; 2) Penza Institute for Advanced Medical Training, Department of Allergology and Immunology with a Course in Dermatovenereology and Cosmetology – Branch Campus of the RMACPE Penza, Russia

Background: The issues of treating atopic dermatitis (AD) during pregnancy present difficulties for doctors, since most drugs used for AD are prohibited for use in pregnant women.
Objective: Evaluation of the results of the combined use of moisturizing and antipruritic dermocosmetics for AD during pregnancy.
Methods: The study involved 76 pregnant women with AD exacerbation. For the treatment of AD, a regimen of topical therapy was developed, including moisturizing and antipruritic dermocosmetics. After 2 and 4 weeks, the SCORAD index, dermatological index of quality of life (DIQOL) and 5D itching scale were assessed.
Results: The developed topical therapy significantly reduced the SCORAD, DIQOL and the itching indices (5D itching scale) (p=0.001). In severe cases, the effectiveness of treatment is reduced, which requires strengthening the basic therapy.
Conclusion: The study showed that the combination of moisturizing and antipruritic dermocosmetics is an effective and safe treatment regimen and can be recommended for the treatment of AD during pregnancy.

Keywords

About the Authors

Yulia A. Kandrashkina, Cand. Sci. (Med.), Senior Lecturer, Penza State University, Penza, Russia; novikova10l@mail.ru, ORCID:
https://orcid.org/0000-0002-5537-5729 (corresponding author)
Ekaterina A. Orlova, Dr. Sci. (Med.), Associate Professor, Head of the Department of Allergology and Immunology with a Course in Dermatovenereology and Cosmetology, Penza Institute for Advanced Medical Training – Branch Campus of the RMACPE Penza, Russia; lisaorl@yandex.ru, ORCID:
https://orcid.org/0000-0002-3902-2018

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