Clinical experience with methylprednisolone aceponate for atopic dermatitis in young children

Botkina A.S., Gumennaya E.R.

1) Pirogov Russian National Research Medical University, Moscow, Russia; 2) Russian Children’s Clinical Hospital – Branch of Pirogov Russian National Research Medical University, Moscow, Russia

Atopic dermatitis, or atopic eczema, is a chronic, relapsing inflammatory skin disease characterized by generalized xerosis, erythematous rash, and intense pruritus. Clinical manifestations vary and depend on the patient’s age. As one of the most common skin diseases worldwide, atopic dermatitis represents a significant clinical and economic burden for patients and their families. Infants present particular challenges in treatment due to the anatomical and physiological characteristics of their skin and the limited range of approved topical anti-inflammatory agents. This article highlights the key aspects of topical corticosteroid use in pediatric dermatology. A clinical example of the effective use of methylprednisolone aceponate in the treatment of infantile atopic dermatitis is presented. Timely and appropriate administration of topical corticosteroids allows for rapid interruption of exacerbations of the skin condition without the development of adverse side effects.

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About the Authors

Aleksandra S. Botkina, Cand. Sci. (Med.), Associate Professor, Department of Hospital Pediatrics named after Academician V.A. Tabolin, Faculty of Pediatrics, Pirogov Russian National Research Medical University, Moscow, Russia; botkina@gmail.com, ORCID: https://orcid.org/0000-0001-6890-2041 (corresponding author)
Elvira R. Gumennaya, Dermatovenerologist, Head of the Dermatovenereology Department, Russian Children’s Clinical Hospital – Branch of the Pirogov Russian National Research Medical University, Moscow, Russia, ORCID: https://orcid.org/0000-0002-8097-2816

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