Type 1 diabetes mellitus and physical activity, the possibilities of using insulin degludec: analysis of clinical cases

O.S. Elsukova

1) Kirov State Medical University, Kirov, Russia; 2) Kirov Clinical Hospital No. 7 named after V.I. Yurlova, Kirov, Russia

Regular physical activity is an integral part of the life of patients with type 1 diabetes mellitus (DM1) due to their young age. Regular aerobic physical activity is associated with improved overall well-being and is a method of preventing cardiovascular diseases. An increased risk of nocturnal hypoglycemia after physical activity is a factor limiting physical activity, especially in young patients and children. Insulin degludec is an analogue of long-acting basal insulin (with a duration of action of more than 42 hours), which has a low variability of action. The ADREM study, conducted using continuous glucose monitoring systems, demonstrated that afternoon aerobic exercise in patients with DM1 treated with insulin degludec did not affect the risk of subsequent nocturnal hypoglycemia. This article reviews a case series of patients with DM1 treated with insulin degludec and regularly engaged in physical activity.

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About the Authors

Olga S. Elsukova, Cand. Sci. (Med.), Associate Professor, Department of Hospital Therapy, Kirov State Medical University; Head of the Endocrinology Department, Regional Endocrinology Center, Kirov Clinical Hospital No. 7 named after V.I. Yurlova, Kirov, Russia; oselsukova@mail.ru, ORCID: https://orcid.org/0000-0002-2341-9491

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