The role of essential phospholipids in the complex therapy of non-alcoholic fatty liver disease: a case-control study

L.V. Tarasova, Yu.V. Tsyganova, I.Yu. Filippov

I.N. Ulyanov Chuvash State University, Cheboksary, Russia

Background. The article demonstrates the potentiation of the clinical effect of essential phospholipids (EPLы) in relation to liver fibrosis in non-alcoholic fatty liver disease (NAFLD), when using complex therapy for NAFLD that meets current specialized clinical guidelines, with the inclusion of EPL in the treatment regimen.
Objective. Comparative assessment of liver stiffness after EPL therapy and without the use of EPL in the context of compliance with specialized clinical guidelines.
Methods. All patients received adequate therapy for NAFLD. In 58 patients, the drug from the EPL group was included in the treatment regimen (experimental group), in 52 patients, the drug was not included (control group).
Results. The presence of a statistically significant difference was determined between patients who received treatment with and without the use of EPL in the regimen.
Conclusion. It is recommended to include EPL in the complex therapy of NAFLD.

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About the Authors

Larisa V. Tarasova, Dr. Sci. (Med.), Head of the Department of Hospital Therapy, I.N. Ulyanov Chuvash State University, Cheboksary, Russia; tlarisagast18@mail.ru, ORCID: https://orcid.org/0000-0003-1496-0689, Scopus Author ID: 35777248600 (corresponding author)
Yulia V. Tsyganova, Candidate of Medical Sciences, Associate Professor of the Department of Hospital Therapy, I.N. Ulyanov Chuvash State University, Cheboksary, Russia; ORCID: https://orcid.org/0000-0002-8339-9496
Igor Yu. Fillipov, senior lecturer of the Department of Hospital Therapy, I.N. Ulyanov Chuvash State University, Cheboksary, Russia; ORCID:
https://orcid.org/0000-0001-7653-1068

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