Clinical features of arterial hypertension against the background of acute respiratory viral infection of various etiologies
Background: Arterial hypertension (AH) is the most common chronic non-infectious disease, against the background of which acute respiratory viral infection (ARVI) can occur.Mordyk A.V., Viktorova I.A., Antipova E.P., Streltsova V.V., Bagisheva N.V., Moiseeva M.V.
Objective: Evaluation of the clinical features of AH in patients with ARVI of various etiologies (COVID-19, influenza, unspecified).
Material and methods: The retrospective comparative study included 373 patients. Patients with AH + ARVI of unspecified etiology (group 1A) – 98 people; AH + COVID-19 (group 1B) – 192 patients; AH + influenza (group 1B) – 12 patients. A group of patients with AH (group 2) was recruited as a control group – 71 patients, comparable by gender, age, AH stage and degree, the presence of complications. Statistical analysis was carried out using the STATISTICA 10.0 software packages.
Results: Against the background of acute respiratory viral infection, regardless of the etiological factor, patients showed an increase in both systolic and diastolic blood pressure (BP), more – with acute respiratory viral infection of unspecified etiology (80%) and COVID-19 (70% of patients), significantly less – with influenza (16.7%). This required treatment adjustments, in particular, a switch from monotherapy to combination antihypertensive therapy. In all patients with arterial hypertension, the course of ARVI was accompanied by tachycardia.
Conclusion: Early intensification of antihypertensive therapy during the development of ARVI of various etiologies in patients with AH history will help maintain control over the disease and prevent the development of vascular accidents.
Keywords
arterial hypertension
acute respiratory viral infection of unknown etiology
influenza
COVID-19
clinical picture
About the Authors
Anna V. Mordyk, Dr. Sci. (Med.), Professor, Head of the Department of Phthisiology, Pulmonology and Infectious Diseases, Omsk State Medical University, Omsk, Russia; amordik@mail.ru, ORCID: https://orcid.org/0000-0001-6196-7256Inna A. Viktorova, Dr. Sci. (Med.), Professor, Head of the Department of Outpatient Therapy and Internal Medicine, Omsk State Medical University, Omsk, Russia; vic-inna@mail.ru, ORCID: https://orcid.org/0000-0001-8728-2722
Ekaterina P. Antipova, Teaching Assistant, Department of Phthisiology, Pulmonology and Infectious Diseases, Omsk State Medical University, Omsk, Russia; eantipova74@mail.ru
Viktoria V. Streltsova, Physician, Poltava Central District Hospital, Omsk Region, Russia; vstrl1611@gmail.com
Natalia V. Bagisheva, Dr. Sci. (Med.), Associate Professor, Department of Outpatient Therapy and Internal Medicine, Omsk State Medical University, Omsk, Russia; ppi100@mail.ru, ORCID: https://orcid.org/0000-0003-3668-1023 (corresponding author)
Marina V. Moiseeva, Cand. Sci. (Med.), Associate Professor, Department of Outpatient Therapy and Internal Medicine, Omsk State Medical University, Omsk, Russia; lisnyak80@mail.ru, ORCID: https://orcid.org/0000-0003-3458-9346