Parry-Romberg progressive facial hemiatrophy

Garayeva Z.Sh., Yusupova L.A., Mavlyutova G.I., Yunusova E.I., Mamleeva A.F.

Kazan State Medical Academy (KSMA) – Branch Campus of the Russian Medical Academy of Continuous Professional Education, Department of Dermatovenereology and Cosmetology, Kazan, Russia
Parry–Romberg progressive facial hemiatrophy is an uncommon, sporadic disorder characterized by progressive hemifacial wasting and atrophy of skin, muscle, and bone, sometimes involving the central nervous system, and manifesting as focal scleroderma. Parry–Romberg syndrome, more common in women without ethnic or geographic predilections, occurs during the first or second decades of life, leading to slow and progressive facial hemiatrophy, predominantly on the left side. The diagnosis of Parry–Romberg syndrome mainly depends on clinical history using imaging studies and histopathological correlation. The article provides data on the etiology, pathogenesis, and clinical picture of the disease. Methods for diagnosing and treating these patients are described in detail.

Keywords

Parry–Romberg progressive facial hemiatrophy
etiology
pathogenesis
clinical picture
diagnosis
treatment

About the Authors

Corresponding author: Luiza A. Yusupova, Dr. Sci. (Med.), Professor, Head of the Department of Dermatovenereology and Cosmetology, Kazan State Medical Academy – Branch Campus of the Russian Medical Academy of Continuous Professional Education, Kazan, Russia; yuluizadoc@hotmail.com

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