Optimization of approaches to the treatment of obesity in patients with type 2 diabetes mellitus

Kurnikova I.A., Chekalina M.S., Ualikhanova A.U.

1) Patrice Lumumba Peoples’ Friendship University of Russia, Moscow, Russia; 2) Central Clinical Hospital of Civil Aviation, Moscow, Russia; 3) Russian Medical Academy of Continuous Professional Education, Moscow, Russia
Diabetes mellitus (DM) and obesity are one of the most common combinations in the structure of comorbid pathology, which is confirmed by numerous epidemiological data. Both of these diseases are based on primary insulin resistance and develop with the participation of largely identical pathological mechanisms. The relationship of pathogenetic mechanisms allows using an integrated approach to prescribing drugs and achieving target glycemic control and weight loss simultaneously. The article presents the main groups of drugs used in the treatment of obesity in diabetic patients with the determination of optimal combinations depending on the characteristics of the DM course, its complications and concomitant diseases.

Keywords

obesity
type 2 diabetes mellitus
hypoglycemic therapy
sibutramine
liraglutide
orlistat

About the Authors

Corresponding author: Irina A. Kurnikova, Dr. Sci. (Med.), Professor, Department of Hospital Therapy with Courses in Endocrinology, Hematology and Clinical Laboratory Diagnostics, Medical Institute, Patrice Lumumba Peoples’ Friendship University of Russia; Russian Medical Academy of Continuous Professional Education, Moscow, Russia; curnikova@yandex.ru

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