Multicenter assessment of the effectiveness of nutritional detoxification process

T.L. Pilat, L.P. Kuzmina, L.M. Bezrukavnikova

1) Izmerov Research Institute of Occupational Health, Moscow, Russia; 2) I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia

Objective. Analysis of the detoxification activity of specialized therapeutic and preventive detoxification products for various types of intoxication.
Methods. The detoxification activity of the carbohydrate drink and jelly for detoxification LEOVIT, as well as the protein-containing product “Detoxification protein shake LEOVIT” was studied. A multicenter assessment of the effectiveness of drinks was carried out in 15 multicenter randomized open clinical trials; 1552 people (1179 in the main group and 373 in the control group) with chronic endogenous intoxication caused by exposure to various hazardous working conditions, as well as infectious and non-infectious environmentally unfavorable factors were examined. A general clinical examination and evaluation of the dynamics of intoxication markers were carried out.
Results. The use of detoxification nutrition in people working in hazardous working conditions and patients with COVID-19 and other viral diseases led to an improvement in biochemical intoxication markers (ESR, CRP, ALT and AST, creatinine), as well as an increase in the main factors of antioxidant protection. In cancer patients, after surgical treatment and taking prescribed therapy, CRP (by 21%) and ESR (by 12%) improved, as well as ALT, AST, GGT, cholesterol, bilirubin and antioxidant protection indicators.
Conclusion. Improvement in intoxication markers in various types of toxic process and improvement in the body’s condition in various pathological processes indicated the universal effect of dietary products for detoxification on the body in case of endo- and exotoxicosis.

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About the Authors

Corresponding author: Tatyana L. Pilat, Dr. Sci. (Med.), Professor, Leading Researcher, Izmerov Research Institute of Occupational Health, Moscow, Russia; tpilat@leovit.ru

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