Metabolic effects of metformin in patients with type 2 diabetes mellitus and new coronavirus infection

I.B. Zhurtova, A.M. Gubachikova, L.S. Aramisova, H.A. Abdul Moati, L.A. Anaeva

Department of Faculty Therapy, Medical Academy, Kabardino-Balkarian State University n.a. Kh.M. Berbekov, Nalchik, Russia
Limited contraindications for use, lack of stimulation of insulin secretion, weight gain and an extremely low risk of hypoglycemic episodes determine the relevance of the use of metformin as a first-line drug in the treatment of type 2 diabetes mellitus (DM2). The potential of metformin is not limited to its use in DM2. Numerous studies determining the pleiotropic effects of metformin have expanded the range of use of this drug. The article presents various metabolic properties of metformin, which have a beneficial effect on the pathogenesis of various pathological conditions, a new coronavirus infection.

Keywords

metformin
metabolic effects
type 2 diabetes mellitus
COVID-19
new coronavirus infection

About the Authors

Corresponding author: Inessa B. Zhurtova, Dr. Sci. (Med.), Professor at the Department of Faculty Therapy, Medical Academy, Kabardino-Balkarian State University n.a. Kh.M. Berbekov, Nalchik, Russia; zhin07@mail.ru

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