Iron deficiency therapy in aesthetic gynecology: current paradigms
Apolikhina I.A., Efendieva Z.N., Serov V.N.
Iron deficiency conditions are particularly significant in obstetrician-gynecologist practice, as they are most common among women of reproductive age with normal menstrual cycles, pregnant women, and women in the perimenopausal period. This article presents an analysis of data from the international literature on the role of iron deficiency and the possibilities for its correction in gynecological practice. Oral iron supplements are currently the first-line treatment for anemia. Today, the rationale for prescribing iron supplements to women with anemia is unquestionable, and the wide range of medications available requires physicians to carefully select the right one, taking into account their efficacy and safety. Research results show that iron protein succinylate is equally effective as iron salts in the treatment of iron deficiency anemia, while oral administration of iron protein succinylate does not result in hepcidin blockade or the development of gastrointestinal adverse effects. Prescribing oral iron supplements at optimal, low therapeutic doses helps minimize side effects and increases iron bioavailability, maintaining high efficacy and patient compliance.
For citations: Apolikhina I.A., Efendieva Z.N., Serov V.N. Iron deficiency therapy in aesthetic gynecology: current paradigms. Pharmateca. 2026;33(4):138-144. (In Russ.). DOI: https://dx.doi.org/10.18565/pharmateca.2026.4.138-144
Authors’ contribution: Apolikhina I.A., Efendieva Z.N. – concept and design of the article. Efendieva Z.N. – work with literature sources, analysis and synthesis of the data obtained, writing the text of the manuscript. Apolikhina I.A., Efendieva Z.N., Serov V.N. – critical revision of the manuscript text, editing. Approval of the final version of the article – all co-authors.
Conflicts of interest: The authors confirm that they have no conflicts of interest to declare.
Funding: The study was conducted without any sponsorship.
Keywords
anemia
iron deficiency
aesthetic gynecology
hepcidin
iron supplements
iron protein succinylate
About the Authors
Inna A. Apolikhina, Dr. Sci. (Med.), Professor, Head of the Department of Aesthetic Gynecology and Rehabilitation, Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology; Professor, Department of Obstetrics, Gynecology, Perinatology, and Reproductive Medicine, Institute of Postgraduate Education, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; ORCID:https://orcid.org/0000-0002-4581-6295
Zulfiya N. Efendieva, Cand. Sci. (Med.), Obstetrician-Gynecologist, MOSITALMED International Medical Center, Moscow, Russia;
efendievaz@yandex.ru, ORCID: https://orcid.org/0000-0002-2978-043X (corresponding author)
Vladimir N. Serov, Dr. Sci. (Med.), Professor, Academician of the Russian Academy of Sciences, President of the Russian Society of Obstetricians and Gynecologists, Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Moscow, Russia
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