Modern skin care methods for children with atopic dermatitis
Mukhortykh V.A., Larkova I.A., Tepoyan A.M., Ramzina A.V., Revyakina V.A.
Background: Atopic dermatitis (AD) remains one of the most pressing issues in pediatric dermatology and allergology. Despite significant advances in understanding the pathogenesis of the disease, which is associated with filaggrin gene mutations and impaired skin barrier function, many treatment issues remain controversial. Selecting effective care methods aimed not only at relieving symptoms but also at ensuring long-term disease control is particularly challenging.
Objective: Systematization of current research data (2020–2025) on basic and supplementary skin care methods for children with AD, offering clinically relevant conclusions for practical application.
Methods: Literature on skin care in children with AD, collected through a search of the Elibrary, PubMed, and MedLine databases for the period 2020–2025, was analyzed using an expert analytical method.
Discussion: Analysis of current data indicates a paradigm shift in the management of patients with AD: from the relief of acute symptoms to proactive long-term therapy aimed at restoring and maintaining the skin barrier. Basic skin care products play a key role in this strategy.
Conclusion: Individualized, appropriate selection of skin care products, taking into account the child’s age, disease severity, and trigger factors, allows for long-term, stable disease remission and significantly improves the quality of life of patients and their families.
For citations: Mukhortykh V.A., Larkova I.A., Tepoyan A.M., Ramzina A.V., Revyakina V.A. Modern skin care methods for children with atopic dermatitis. Pharmateca. 2026;33(3):24-31. (In Russ.). DOI: https://dx.doi.org/10.18565/pharmateca.2026.3.24-31
Authors’ contribution: Tepoyan A.M., Mukhortykh V.A. – creation of the concept, construction of sections of the work. Tepoyan A.M., Mukhortykh V.A., Larkova I.A., Ramzina A.V. – work with literature sources, analysis and generalization of the data obtained, writing the text of the manuscript. Tepoyan A.M., Larkova I.A., Revyakina V.A. – critical revision of the text of the manuscript. Approval of the final version of the article, responsibility for the integrity of all parts of the article – all co-authors.
All authors approved the final version of the article before publication and agreed to be accountable for all aspects of the work, including ensuring that any questions related to the accuracy or integrity of any part of the work have been appropriately investigated and resolved.
Conflicts of interest: The authors confirm that they have no conflicts of interest to declare.
Funding: This work was conducted as part of the state assignment of the Federal Research Center for Nutrition and Biotechnology No. FGMF-2025-0003.
Keywords
atopic dermatitis
children
emollients
hygiene procedures
disinfectant baths
wet wraps
topical external therapy
filaggrin
About the Authors
Valery A. Mukhortykh, Allergist-Immunologist, Federal Scientific and Clinical Center for Children and Adolescents; A.I. Burnazyan Federal Medical Biophysical Center; Federal Research Center for Nutrition, Biotechnology, and Food Safety, Moscow, Russia; valera-89@yandex.ru,ORCID: https://orcid.org/0000-0001-8549-9493 (corresponding author)
I.A. Larkova, Federal Research Center for Nutrition, Biotechnology, and Food Safety; National Medical Research Center for Children’s Health, Moscow, Russia; ORCID: https://orcid.org/0000-0001-7640-0754
A.M. Tepoyan, Federal Scientific and Clinical Center for Children and Adolescents, Moscow, Russia; https://orcid.org/0009-0005-0316-8209
A.V. Ramzina, Chaika Clinic, Moscow, Russia; ORCID: https://orcid.org/0009-0000-4227-5844
V.A. Revyakina, Federal Research Center for Nutrition, Biotechnology, and Food Safety; National Medical Research Center for Children’s Health, Moscow, Russia; ORCID: https://orcid.org/0000-0002-1149-7927
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