Ways to improve treatment adherence: a comprehensive approach and practical tools for physicians

Sychev D.A., Arutyunov G.P., Dzgoeva F.Kh., Yezhov M.V., Ilchishina T.A., Ionin V.A., Kucheryavy Yu.A., Lopatin Z.V., Marchenkova L.A., Nikolaev P.I., Podzolkova N.M., Raikhelson K.L., Smetnik A.A., Usov G.M., Shishkova V.N., Yakubov E.Z.

GROUP OF AUTHORS:
Dmitry A. Sychev, Dr. Sci. (Med.), Professor, Professor of the Russian Academy of Sciences, Academician of the Russian Academy of Sciences, Scientific Director of the World-Class Genomic Research Center “Center for Predictive Genetics, Pharmacogenetics, and Personalized Therapy”, B.V. Petrovsky Russian Scientific Center of Surgery; Head of the Department of Clinical Pharmacology and Therapy named after B.E. Votchal, Russian Medical Academy of Continuous Professional Education, Moscow, Russia
Grigory P. Arutyunov, Corresponding Member of the Russian Academy of Sciences, Professor, Dr. Sci, (Med.), Head of the Department of Therapy, Pirogov Russian National Research Medical University, Laureate of the Russian Federation Government Prize, Honored Doctor of the Russian Federation, Vice-President of the Russian Society of Cardiologists, Vice-President of the Russian Scientific Society of Therapists, President of the Eurasian Association of Therapists (EAT), Moscow, Russia
Fatima Kh. Dzgoeva, Cand. Sci. (Med.), Endocrinologist, Nutritionist, Associate Professor, Department of Diabetology and Dietetics, Institute of High and Continuous Professional Education, Head of the Department of Dietetic Care, National Medical Research Center of Endocrinology, Moscow, Russia
Marat V. Yezhov, Dr. Sci, (Med.), Professor, Head of the Laboratory of Lipid Metabolism Disorders, A.L. Myasnikov Research Institute of Clinical Cardiology, E.I. Chazov National Medical Research Center of Cardiology; President of the National Atherosclerosis Society, Member of the European Society of Cardiology, European Atherosclerosis Society, International Atherosclerosis Society, American Heart Association, and American College of Cardiology, Moscow, Russia
Tatyana A. Ilchishina, Cand. Sci. (Med.), Chief Gastroenterologist, Multidisciplinary Medical Holding SM-Clinic North-West, St. Petersburg, Russia
Valery A. Ionin, Dr. Sci, (Med.), Professor, Department of Faculty Therapy with a Course in Endocrinology and Cardiology with the G.F. Lang Clinic, Senior Researcher, Research Institute of Cardiovascular Diseases, National Clinical Research Center, Pavlov First Saint Petersburg State Medical University, Freelance Head of the Clinical Diagnostic Center of the Arrhythmology, St. Petersburg, Russia
Yury A. Kucheryavy, Cand. Sci. (Med.), Associate Professor, Scientific Director of the Gastroenterology Department, Ilyinskaya Hospital, Moscow, Russia
Zakhar V. Lopatin, Cand. Sci. (Med.), Vice-Rector for Academic Affairs, Russian Medical Academy of Continuous Professional Education, Acting Head of the Department of Organization and Management of Medical Education, Moscow, Russia
Larisa A. Marchenkova, Dr. Sci, (Med.), Associate Professor, Head of the Research Department, Professor, Department of Restorative Medicine, Physical Therapy, and Medical Rehabilitation, National Medical Research Center of Rehabilitation and Balneology, Moscow, Russia
Pavel I. Nikolaev, Cand. Sci. (Psychology), General Director, All Brains LLC, Member of the Supreme Expert Council of the Business Training Department at the Academy of Social Technologies, Moscow, Russia
Natalya M. Podzolkova, Dr. Sci, (Med.), Professor, Head of the Department of Obstetrics and Gynecology, Russian Medical Academy of Continuous Professional Education; Leading Researcher.S.P. Botkin Moscow Multidisciplinary Scientific and Clinical Center, Moscow Healthcare Department, Moscow, Russia
Karina L. Raikhelson, Dr. Sci, (Med.), Professor, Clinical Research and Educational  Center of Gastroenterology and Dietetics, St. Petersburg State University; Professor, Department of General Medical Practice (Family Medicine), Pavlov First Saint Petersburg Medical University, St. Petersburg, Russia
Antonina A. Smetnik, Cand. Sci. (Med.), Head of the Department of Gynecological Endocrinology, V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, President of the Russian Society of Specialists in Gynecological Endocrinology and Menopause (RSSGEM); Advisor to the European Menopause and Andropause Society (EMAS); Member of the Steering Committee for Affiliated Associations at the International Menopause Society (IMS), Moscow, Russia
Grigory M. Usov, Cand. Sci. (Med.),, Associate Professor, Psychiatrist of the Highest Qualification Category, Psychotherapist, Head of the Department of Psychiatry and Medical Psychology, Omsk State Medical University; Member of the Board of the Russian Society of Psychiatrists, Omsk, Russia
Veronika N. Shishkova, Dr. Sci. (Med.), Professor, Department of Outpatient Therapy, Vladimirsky Moscow Regional Scientific Research Institute; Professor, Department of Neuro- and Pathopsychology, L.S. Vygotsky Institute of Psychology, Russian State University for the Humanities, Moscow, Russia
Eduard Z. Yakupov, Neurologist, Dr. Sci, (Med.), Professor, Honored Doctor of the Republic of Tatarstan, Founder and Director of the Neuroclinic, Professor Yakupov Educational Center, and the Online Project “Virtual Medical Academy,” Kazan, Russia

Treatment adherence is one of the key modifiable factors determining the achievement of clinical goals in chronic and socially significant diseases. The Interdisciplinary Expert Council examined the issue of treatment adherence and proposed a set of measures to its improvement with the aim of reducing the incidence of adverse outcomes in socially significant diseases, increasing life expectancy and quality of life, and optimizing healthcare costs. The Expert Council proposed a number of practical tools that can be integrated into routine doctor visits. Without additional time investment, they have proven effectiveness and can have a significant impact on the quality of communication with patients and the development of adherence. Recommendations for organizational measures, personnel training, improving the status of physicians, and changes at the public policy level are formulated.

For citations: Sychev D.A., Arutyunov G.P., Dzgoeva F.Kh., Yezhov M.V., Ilchishina T.A., Ionin V.A., Kucheryavy Yu.A., Lopatin Z.V., Marchenkova L.A., Nikolaev P.I., Podzolkova N.M., Raikhelson K.L., Smetnik A.A., Usov G.M., Shishkova V.N., Yakubov E.Z. Ways to improve treatment adherence: a comprehensive approach and practical tools for physicians. Pharmateca. 2026;33(1):188-205. (In Russ.). DOI: https://dx.doi.org/10.18565/pharmateca.2026.1.188-205
Conflicts of interest: The authors confirm that they have no conflicts of interest to declare.

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