Occupational chronic obstructive pulmonary disease in its isolated and comorbid course from the perspective of assessing the psychological profile and quality of life
Babanov S.A., Strizhakov L.A., Vostroknutova M.Yu., Lavrentyeva N.E., Vasina I.N., Babanov A.S., Artemyeva M.S., Vostrikova M.V.
Background: Evaluation of clinical data, psychological profile, and quality of life (QOL) in occupational chronic obstructive pulmonary disease (oCOPD), both with isolated and comorbid course, opens up new possibilities for assessing the development, predicting the course, and personalizing the pharmacotherapy of COPD, as well as for developing individualized strategies for its primary and secondary prevention.
Objective: Determination of the psychological characteristics and QOL in COPD, both isolated and in combination with arterial hypertension (AH).
Material and methods: The study involved 175 patients and 60 controls: Group 1 (control) – 60 healthy volunteers, Group 2 – 35 patients with stage 1 oCOPD (oCOPD I), Group 3 – 50 patients with stage 2 oCOPD, Group 4 – 40 patients with a combination of stage 2 oCOPD and AH, Group 5 – 50 patients with isolated AH. All patients were tested using three methods: the Buss-Durkee Hostility Inventory and the Plutchik-Kellerman-Conte Life Style Index (LSI). Quality of life was also assessed using the SF-36 Health Status Survey. Group data were evaluated using a one-way analysis of variance with between-group comparisons using Dunnett’s test.
Results: For the first time, the characteristics of psychological manifestations and QOL in oCOPD of varying severity, both in isolation and in combination with AH, have been identified.
Conclusion: Exposure to occupational dust is a stress factor leading to the development of severe psychoemotional disorders in oCOPD, both isolated and in combination with AH. We believe that a comprehensive psychological examination, including consultation with a psychologist and the use of the Buss-Durkee Hostility Inventory and the LSI method, as well as QOL assessment, is essential. A QOL assessment was also conducted using the SF-36 questionnaire as part of a program of in-depth periodic medical examinations for individuals working with chemical and fibrogenic industrial aerosols potentially associated with the development of occupational chronic obstructive pulmonary disease (oCOPD). This assessment was also part of a program for providing medical care to patients with COPD, both isolated and comorbid with AH, at pulmonology centers and occupational pathology centers at the federal and regional levels. This assessment took into account the identified psychological changes, decreased QOL, and the need for timely psychological intervention, including the use of pharmacological agents.
For citations: Babanov S.A., Strizhakov L.A., Vostroknutova M.Yu., Lavrentyeva N.E., Vasina I.N., Babanov A.S., Artemyeva M.S., Vostrikova M.V. Occupational chronic obstructive pulmonary disease in its isolated and comorbid course from the perspective of assessing the psychological profile and quality of life. Pharmateca. 2025;32(9):40-48. (In Russ.). DOI: https://dx.doi.org/10.18565/pharmateca.2025.9.40-48
Authors’ contribution: Babanov S.A., Vostroknutova M.Yu. – concept and design of the study, collection of material. Babanov S.A., Vostroknutova M.Yu., Strizhakov L.A., Lavrentyeva N.E. Vasina I.N., Babanov A.S., Artemyeva M.S., Vostrikova M.V. – statistical data processing, writing the text of the article, editing, preparation for publication.
Conflicts of interest: The authors confirm that they have no conflicts of interest to declare.
Funding: The study was conducted without any sponsorship.
Ethical Approval: The study was approved by the Bioethics Committee of the Samara State Medical University, Ministry of Health of the Russian Federation.
Patient Consent for Publication: Each study participant provided informed, voluntary, written consent to participate in the study and the publication of their personal medical information in anonymized form.
Authors’ Data Sharing Statement: The data supporting the findings of this study are available upon request from the corresponding author after approval from the principal investigator.
Keywords
occupational chronic obstructive pulmonary disease
arterial hypertension
psychological profile
quality of life
About the Authors
S.A. Babanov, Dr. Sci. (Med.), Professor, Head of the V.V. Kosarev Department of Occupational Diseases and Clinical Pharmacology, Samara State Medical University, Samara, Russia; s.a.babanov@mail.ru, ORCID: https://orcid.org/0000-0002-1667-737X (corresponding author)L.A. Strizhakov, Izmerov Research Institute of Occupational Health, Moscow, Russia
M.Yu. Vostroknutova, Samara City Hospital No. 5, Samara, Russia
N.E. Lavrentyeva, Samara State Medical University, Samara, Russia
I.N. Vasina, Samara City Hospital No. 5, Samara, Russia
A.S. Babanov, Samara State Medical University, Samara, Russia
M.S. Artemyeva, Samara State Medical University, Samara, Russia
M.V. Vostrikova, Samara City Hospital No. 7, Samara, Russia
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