Current principles of antibiotic therapy in the management of patients with chlamydial infection

Kruglova L.S., Rubtsova L.A., Kruglova M.S.

1) Central State Medical Academy of the Administrative Directorate of the President of the Russian Federation, Moscow, Russia; 2) Institute of Plastic Surgery and Cosmetology, Moscow, Russia; 3) I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia

Given the increasing global incidence of urogenital chlamydial infection caused by Chlamydia trachomatis and the challenges of its diagnosis, choosing an effective therapy is particularly important. Currently, doxycycline is the first-line drug, supported by its pharmacokinetic advantages: its ability to create and maintain long-term concentrations in the tissues of the urogenital tract and rectum necessary for successful eradication of the pathogen. High efficacy, favorable tolerability profile, and ability to treat extragenital foci of infection make Doxycycline EXPRESS the drug of choice for the treatment and post-exposure prophylaxis of chlamydial infection.

For citations: Kruglova L.S., Rubtsova L.A., Kruglova M.S. Current principles of antibiotic therapy in the management of patients with chlamydial infection. Pharmateca. 2025;32(10):39-44. (In Russ.). DOI: https://dx.doi.org/10.18565/pharmateca.2025.10.39-44

Authors’ contribution: All authors made an equivalent contribution to the preparation of the publication.
Conflicts of interest: The authors confirm that they have no conflicts of interest to declare.
Funding: The study was conducted without any sponsorship.

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About the Authors

Larisa S. Kruglova, Dr. Sci. (Med.), Professor, Head of the Department of Dermatovenereology and Cosmetology, Rector, Central State Medical Academy of the Administrative Directorate of the President of the Russian Federation, Moscow, Russia; kruglovals@mail.ru, ORCID: https://orcid.org/0000-0002-5044-5265
Lyubov A. Rubtsova, Central State Medical Academy of the Administrative Directorate of the President of the Russian Federation; Institute of Plastic Surgery and Cosmetology, Moscow, Russia; lubovrubtz@gmail.com, ORCID: https://orcid.org/0000-0001-5245-0394 (corresponding author)
Maria S. Kruglova, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; kruglovamashulka@gmail.com, ORCID: https://orcid.org/0000-0002-3190-7460

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