Modern aspects of detection and monitoring of preclinical stages of type 1 diabetes mellitus in children

T.V. Varlamova, N.N. Vezikova

Petrozavodsk State University, Petrozavodsk, Russia

Type 1 diabetes mellitus (DM1) is one of the most common endocrine diseases in children. DM1 develops as a result of the interaction of a predisposing genetic background and epigenetic factors. Identification of patients at risk of developing DM1 is the key to developing strategies to prevent the development of the disease. Autoantibody-based screening provides information on the current DM1 stage, the time before the risk of developing stage 3 DM1. The introduction of screening for DM1 has potential benefits, namely, a decrease in the development of diabetic ketoacidosis, a decrease in stress on the part of parents and children when making a diagnosis, and the possibility of better psychological adaptation.

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About the Authors

Tatyana V. Varlamova, Cand. Sci. (Med.), Associate Professor, Petrozavodsk State University, Medical Institute named after prof. A.P. Zilber, Petrozavodsk, Russia; varlamova@sampo.ru, examlpe@address.ru, ORCID: https://orcid.org/0000-0001-5617-8893, Scopus Author
ID: 58819203900 (corresponding author)
N.N. Vezikova, Petrozavodsk State University, Petrozavodsk, Russia; ORCID: https://orcid.org/0000-0002-8901-3363, Scopus Author
ID: 6505871479

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