The role of skin microbiota in the development of atopic dermatitis in pregnant women and their newborns: prospects for diagnosis and therapy

Orlova E.A., Kulieva O.A., Kandrashkina Yu.A., Levashova O.A., Nikolashina O.E., Rybalkin S.B.

1) Penza Institute for Advanced Medical Training – branch of the Russian Medical Academy of Continuous Professional Education, Department of Allergology and Immunology with a Course in Dermatovenereology and Cosmetology, Penza, Russia; 2) Penza Institute for Advanced Medical Training – branch of the Russian Medical Academy of Continuous Professional Education, Department of Medical Microbiology and Laboratory Medicine, Penza, Russia; 3) Penza State University, Department of Obstetrics and Gynecology, Penza, Russia; 4) Penza State University, Department of Microbiology, Epidemiology and Infectious Diseases, Penza, Russia; 5) Penza Regional Clinical Center for Specialized Types of Medical Care, Outpatient Department, Penza, Russia

This review is devoted to the study of the skin microbiome, its role in the pathology of atopic dermatitis (AD) and changes in the microbiota during pregnancy and in newborns. It is noted that children born vaginally often have a healthier microbiota compared to those born by cesarean section. The importance of maternal microflora in the formation of the child’s microbiome is shown. The key factors that form the skin microbiome of mother-child pairs are considered. The effect of topical skin care products on this parameter is described. The article emphasizes the importance of further research into the skin microbiome for understanding the pathogenesis of AD and developing effective methods of prevention and treatment.

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About the Authors

E.A. Orlova, Penza Institute for Advanced Medical Training – branch of the Russian Medical Academy of Continuous Professional Education, Department of Allergology and Immunology with a Course in Dermatovenereology and Cosmetology, Penza, Russia; ORCID: http://orcid.org/0000-0002-3902-2018
Oksana A. Kulieva, Assistant, Department of Medical Microbiology and Laboratory Medicine, Penza Institute for Advanced Medical Training – branch of the Russian Medical Academy of Continuous Professional Education, Penza, Russia; golikowa.oksana@yandex.ru, ORCID: http://orcid.com/0009-0004-2452-747X, eLibrary SPIN: 4855-4432 (corresponding author)
Yu.A. Kandrashkina, Penza State University, Department of Obstetrics and Gynecology, Penza, Russia; ORCID: http://orcid.org/0000-0002-5537-5729
O.A. Levashova, Penza Institute for Advanced Medical Training – branch of the Russian Medical Academy of Continuous Professional Education, Department of Medical Microbiology and Laboratory Medicine, Penza, Russia; ORCID: http://orcid.org/0000-0002-8440-6598
O.E. Nikolashina, Penza State University, Department of Microbiology, Epidemiology, and Infectious Diseases; Penza Regional Clinical Center for Specialized Types of Medical Care, Outpatient Department, Penza, Russia; ORCID: https://orcid.org/0009-0001-6903-2356
S.B. Rybalkin, Penza State University, Department of Microbiology, Epidemiology, and Infectious Diseases; Penza Regional Clinical Center for Specialized Types of Medical Care, Outpatient Department, Penza, Russia; ORCID: https://orcid.org/0009-0009-7452-9787

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