The role of genetic risk in assessing cardiovascular prognosis in patients with long QT syndrome

Iskenderov B.G., Lokhina T.V., Berenstein N.V.

Department of Therapy, Cardiology, Functional Diagnostics and Rheumatology, Penza Institute for Postgraduate Medical Education – Branch Campus of the RMACPE, Penza, Russia

Congenital long QT syndrome (LQTS) is the most common primary electrical heart disease, characterized by an increased risk of polymorphic ventricular tachycardia and sudden cardiac death. The review article describes in detail the modern architecture of LQTS, approaches to stratification of cardiovascular prognosis and analysis of risk markers, including the role of genetic factors. In this regard, it is of interest to introduce new highly informative electrocardiographic risk markers for clinical outcomes in patients with congenital LQTS.

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About the Authors

Corresponding author: Bakhram G. Iskenderov, Dr. Sci. (Med.), Professor, Head of the Department of Therapy, Cardiology, Functional Diagnostics and Rheumatology, Penza Institute for Postgraduate Medical Education – Branch Campus of the RMACPE, Penza, Russia; iskenderovbg@mail.ru

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