Mexidol: Main Neuropsychotropic Effects And Mechanisms Of Action
Mexidol: main neuropsychotropic effects and mechanisms of actionT.A. Voronina
The paper presents the review data for the Meksidol pharmacological effects and pharmacokinetics. We considered the neuroprotective, anti-ischemic, nootropic, antistress, anxiolytic, anticonvulsant, anti-alcohol, antiatherogenic, and geroprotective effects of Meksidol. Special attention is given to the Meksidol effects in the treatment of neurodegeneration diseases, especially acute and chronic cerebral circulation disorders. The data for multicomponent mechanism of Meksidol action with important antioxidant and membranotropic effects, the ability to modulation of the receptors and membrane-bound enzymes enzymes function, and restoration of neuromediator balance are presented.
Keywords
Meksidol
antioxidants
free radicals
lipid peroxidation
succinate
neuropsychotropic action