A case report of partial erythroderma during Hodgkin lymphoma therapy

Reshetnikova T.B., German R.V., Nemchaninova O.B., Pozdnyakova O.N.

Novosibirsk State Medical University, Novosibirsk, Russia

Background: Due to its high metabolic rate, the skin is one of the main target organs for the development of chemotherapy-associated side effects. The effects range from the most common but nonspecific rashes to rare but more typical skin lesions. The physician’s task is to recognize patterns of manifestations that reflect the skin’s response to drug therapy, identify a likely trigger, and determine whether the reaction is dose-dependent toxicity [1]. Skin toxicity is a common problem in the treatment of hemoblastoses. Dermatological side effects cause physical and psychological discomfort and can also serve as a reason for abandoning therapy for the underlying hematological disease [2]. With the expansion of the range of therapeutic options for antitumor therapy, dermatological side effects are also becoming more diverse and complex for the physician [2].
Description of the clinical case: The article presents a clinical observation of a patient with developed partial erythroderma of presumably psoriatic genesis against the background of combination therapy for Hodgkin’s lymphoma.
Conclusion: The presented case allows to increase physicians’ awareness of the clinical diversity of manifestations of skin toxicity against the background of antitumor therapy for hemoblastoses.

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About the Authors

T.B. Reshetnikova, Dr. Sci. (Med.), Professor, Department of Dermatovenereology and Cosmetology, Novosibirsk State Medical University, Novosibirsk, Russia; tatyanaresh@mail.ru, ORCID: https://orcid.org/0000-0002-6156-0875
R.V. German, Postgraduate Student, Department of Dermatovenereology and Cosmetology, Novosibirsk State Medical University, Novosibirsk, Russia; rv.german@mail.ru, ORCID: https://orcid.org/0009-0008-0462-8109 (corresponding author)
O.B. Nemchaninova, Dr. Sci. (Med.), Professor, Head of the Department of Dermatovenereology and Cosmetology, Novosibirsk State Medical University, Novosibirsk, Russia; obnemchaninova@mail.ru, ORCID: https://orcid.org/0000-0002-5961-6980
O.N. Pozdnyakova, Dr. Sci. (Med.), Professor, Department of Dermatovenereology and Cosmetology, Novosibirsk State Medical University, Novosibirsk, Russia; pozdnyakova.o.n@mail.ru, ORCID: https://orcid.org/0000-0003-1389-1001

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