Spontaneous regression of hormonally inactive pituitary adenoma: a clinical case and literature review

N.I. Mikhailov, A.M. Zaitsev, O.N. Kirsanova, S.A. Kisariev

P. Herzen Moscow Oncology Research Institute, Branch of the National Medical Research Radiology Center of the Ministry of Health of the Russian Federation, Moscow, Russia

Background. Pituitary adenomas are benign neoplasms, which account for up to 15% of intracranial tumors. Most pituitary macroadenomas today are subject to surgical treatment, and therefore information on the natural course of these tumors is scarce.
Description of the clinical case. In patient B., born in 1990, an endosuprasellar tumor was detected on MRI of the brain performed for headache. Given the absence of neurological symptoms, the patient was kept under follow-up. MRI control 2 months after showed a decrease in the size of the tumor, 4 months after - almost complete regression.
Conclusion. Spontaneous regression of pituitary adenomas is considered a rare but potentially possible outcome. In this regard, when planning the surgical treatment of pituitary adenomas, it is necessary to carefully study all preoperative imaging to confirm that the tumor has not regressed spontaneously.

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About the Authors

Corresponding author: Nikita I. Mikhailov, Cand. Sci. (Med.), Neurosurgeon, P. Herzen Moscow Oncology Research Institute, Branch of the National Medical Research Radiology Center of the Ministry of Health of the Russian Federation, Moscow, Russia; Michailov_md@mail.ru

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