The use of propafenone in the treatment of atrial fibrillation

Syrov A.V.

Peoples’ Friendship University of Russia named after Patrice Lumumba, Moscow, Russia

Atrial fibrillation (AF) is the most common heart rhythm disorder requiring treatment, the prevalence of which increases with age. Pharmacological drugs are the first-line therapy for AF treatment. Antiarrhythmic drugs (AADs) are used as emergency therapy to terminate recently developed AF and to maintain sinus rhythm as a planned therapy to prevent recurrence of arrhythmia. The review presents data on the most commonly used AAD in clinical practice for the treatment of AF, propafenone. A distinctive feature of propafenone is the possibility of its use at all stages of medical care: outpatient, emergency, inpatient, both orally and intravenously. The drug can be used both to interrupt paroxysmal AF and to maintain sinus rhythm in planned therapy.

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About the Authors

Corresponding author: Andrey V. Syrov, Cand. Sci. (Med.), Associate Professor, Department of General Medical Practice, Medical Institute, 
Peoples’ Friendship University of Russia named after Patrice Lumumba, Moscow, Russia; syrman2002_1@yahoo.com; ORCID: 
https://orcid.org/0000-0002-2536-5781

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