Efficacy of intraovarian administration of platelet-rich plasma in infertility treatment programs using assisted reproductive technologies

Yu.A. Fortygina, E.V. Kulakova, N.P. Makarova, T.A. Teterina, I.A. Apolikhina, E.A. Kalinina

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology., Moscow, Russia

Background. Current trends in delayed motherhood dictate the search for new solutions to maintain women’s reproductive health. An increase in the average age of primiparas up to 30–40 years is unshakably accompanied by physiological aging of the ovaries and, accordingly, a decrease in the quality and number of germ cells.
Material and methods. The article highlights the results of the introduction of autologous platelet-rich plasma into the ovary. The analysis of clinical and anamnestic characteristics of patients, hormonal profile and the effectiveness of the procedure in preparation for in vitro fertilization programs was carried out.
Conclusion. The effectiveness of the autologous administration of platelet-rich plasma opens up new opportunities for patients with reduced ovarian reserve and certain hormonal profile parameters, but further research is required in this area.

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About the Authors

Corresponding author: Elena V. Kulakova, Dr. Sci. (Med.), Senior Researcher at the Department of Assistive Technologies in the Treatment of 
Infertility n.a. Professor B.V. Leonov, V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia; e_kulakova@oparina4.ru

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